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SLC9B2

Sodium–hydrogen antiporters, such as NHEDC2, convert the proton motive force established by the respiratory chain or the F1F0 mitochondrial ATPase into sodium gradients that drive other energy-requiring processes, transduce environmental signals ...

                                               

SMARCA5

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 is a protein that in humans is encoded by the SMARCA5 gene.

                                               

SMARCAD1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 is a protein that in humans is encoded by the SMARCAD1 gene. The correct expression of SMARCAD1 might be important for the development of ...

                                               

SOD3

Extracellular superoxide dismutase is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of SOD superoxide dismutase family protein. Sods are antioxidant enzymes that catalyze dismutate two superoxide radicals into h ...

                                               

Solute carrier family 10 member 4

Solute carrier family 10 member 4 is a protein that in humans is encoded by the SLC10A4 gene. In mice, it appears to promote acidification of synaptic vesicles containing monoamines, enhancing their uptake, and is co-expressed with VMAT2 and VAChT.

                                               

SORBS2

ArgBP2 protein, also referred to as Sorbin and SH3 domain-containing protein 2 is a protein that in humans is encoded by the SORBS2 gene. ArgBP2 belongs to the a small family of adaptor proteins having sorbin homology domains. ArgBP2 is highly ab ...

                                               

SRD5A3

Steroid 5-alpha-reductase 3, also known as 3-oxo-5-alpha-steroid 4-dehydrogenase 3, is an enzyme that in humans is encoded by the SRD5A3 gene. It is one of three forms of 5α-reductase.

                                               

STAP1

The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a positive feedback loo ...

                                               

STATH

Statherin is a protein in humans that is encoded by the STATH gene. It prevents the precipitation of calcium phosphate in saliva, maintaining a high calcium level in saliva available for remineralisation of tooth enamel and high phosphate levels ...

                                               

STIM2

Stromal interaction molecule 2 is a protein that in humans is encoded by the STIM2 gene. This gene is a member of the stromal interaction molecules Stim family, which consists of only two members, together with its homologue STIM1, and probably a ...

                                               

Stimulator of chondrogenesis 1

Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly inclu ...

                                               

SULT1B1

Sulfotransferase family cytosolic 1B member 1 is an enzyme that in humans is encoded by the SULT1B1 gene. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These cytosol ...

                                               

SULT1E1

Estrogen sulfotransferase is an enzyme that in humans is encoded by the SULT1E1 gene. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These cytosolic enzymes differ in ...

                                               

SYNPO2

Myopodin protein, also called Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene. Myopodin is expressed in cardiac, smooth muscle and skeletal muscle, and localizes to Z-disc structures.

                                               

TACC3

Transforming acidic coiled-coil-containing protein 3 is a protein that in humans is encoded by the TACC3 gene. The function of this gene has not yet been determined, however, he suggested that it may be involved in cellular growth and differentia ...

                                               

TBC1D1

TBC1 domain family member 1 is a protein that in humans is encoded by the TBC1D1 gene. TBC1D1-member family of proteins sharing a 180 - to 200-amino acid TBC domain, it is assumed that the role in the regulation of cellular growth and differentia ...

                                               

TENM3

Teneurin-3, also known as Ten-m3, Odz3, Ten-m/Odz3, Tenascin-like molecule major 3 or Teneurin transmembrane protein 3, is a protein that, in humans, is encoded by the TENM3, or ODZ3, gene. Ten-m3 is a ~300 kDa type II transmembrane glycoprotein ...

                                               

Tet methylcytosine dioxygenase 2

Tet methylcytosine dioxygenase 2 is a human gene. It resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of heterozygosity in patients with diverse myeloid malignancies.

                                               

TLL1

Tolloid-like protein 1 is a protein that in humans is encoded by the TLL1 gene. This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. A similar protein in mice is required during heart ...

                                               

TLR 1

TLR 1 is a member of the toll-like receptor family of pattern recognition receptors of the innate immune system. TLR1 recognizes pathogen-associated molecular pattern with a specificity for gram-positive bacteria. TLR1 has also been designated as ...

                                               

TLR3

Toll-like receptor 3 also known as CD283 is a protein that in humans is encoded by the TLR3 gene. TLR3 is a member of the toll-like receptor family of pattern recognition receptors of the innate immune system.

                                               

TLR2

Toll-like receptor 2 also known as TLR2 is a protein that in humans is encoded by the TLR2 gene. TLR2 has also been designated as CD282. TLR2 is one of the toll-like receptors and plays a role in the immune system. TLR2 is a membrane protein, a r ...

                                               

TLR10

Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. TLR10 has also been designated as CD290. TLR10 has not been extensively studied because it is a pseudogene in mice, though all other mammalian species contain an inta ...

                                               

TMPRSS11D

Transmembrane protease, serine 11D is an enzyme that in humans is encoded by the TMPRSS11D gene. This gene encodes a trypsin-like serine protease released from the submucosal serous glands in the mucosa. This is a type II integral membrane protei ...

                                               

Trafficking protein particle complex 11

The protein encoded by this gene is a subunit of the TRAPP transport protein particle tethering complex, which functions in intracellular vesicle trafficking. This subunit is involved in early stage endoplasmic reticulum-to-Golgi vesicle transpor ...

                                               

Transmembrane Protein 175

Transmembrane Protein 175, or TMEM175, is a transmembrane protein that is thought to be an endolysosomal potassium channel. It is predicted to have many orthologs across eukaryotes.

                                               

Tryptophan 2.3-dioxygenase

In enzymology, tryptophan 2.3-dioxygenase is a heme enzyme that catalyzes the oxidation of L-tryptophan to N-formyl-L-kynurenine, as the first and rate-limiting step of the kynurenine pathway. L-tryptophan + O 2 ⇌ {\displaystyle \rightleftharpoon ...

                                               

UDP-glucose 6-dehydrogenase

UDP-glucose 6-dehydrogenase is a cytosolic enzyme that in humans is encoded by the UGDH gene. The protein encoded by this gene converts UDP-Glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyal ...

                                               

UGT2A1

The olfactory neuroepithelium, which lines the posterior nasal cavity, is exposed to a wide range of odorants and airborne toxic compounds. Odorants, which are mostly small lipophilic molecules, enter the mucus flow and reach the odorant receptor ...

                                               

UGT2A2

The olfactory neuroepithelium, which lines the posterior nasal cavity, is exposed to a wide range of odorants and airborne toxic compounds. Odorants, which are mostly small lipophilic molecules, enter the mucus flow and reach the odorant receptor ...

                                               

UGT2B4

UGT2B4 is mainly involved in the glucuronidation of hyodeoxycholic acid, a bile acid, and catechol-estrogens, such as 17-epiestriol and 4-hydroxy-estrone. The expression of UGT2B4 enzyme are activated by farnesoid x receptor yet, a nuclear recept ...

                                               

UGT2B7

UGT2B7 is a phase II metabolism isoenzyme found to be active in the liver, kidneys, epithelial cells of the lower gastrointestinal tract and also has been reported in the brain. In humans, UDP-Glucuronosyltransferase-2B7 is encoded by the UGT2B7 ...

                                               

UGT2B17

UDP-glucuronosyltransferase 2B17 is an enzyme that in humans is encoded by the UGT2B17 gene. UGT2B17 belongs to the family of UDP-glucuronosyltransferases UHC, KF 2.4.1.17, enzymes that catalyze the transfer of glucuronic acid from uridine diphos ...

                                               

UGT8

Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides c ...

                                               

UNC5C

Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene. This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct continuation of the axons and cell migration during neura ...

                                               

USP53

Inactive ubiquitin carboxyl-terminal hydrolase 53 is a protein that in humans is encoded by the USP53 gene. Although USP53 is classified as a deubiquitinating enzyme, based on sequence homology with other proteases of this group, it lacks the fun ...

                                               

WDFY3

WD repeat and FYVE domain-containing protein 3 is a protein that in humans is encoded by the WDFY3 gene. This gene encodes a protein which contains WD-repeats and a FYVE domain. Several alternative spliced variants of the transcript have been fou ...

                                               

WDR1

WD repeat-containing protein 1 is a protein that in humans is encoded by the WDR1 gene. This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30 - to 40-amino acid Domains containing several conservative residues, most ...

                                               

WFS1

This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Wolframin appears to function as a cation ...

                                               

WHSC1

Probable histone-lysine N-methyltransferase NSD2 is an enzyme that in humans is encoded by the WHSC1 gene. This gene encodes a protein that contains at present four domains in other proteins development: a PWWP domain, HMG box, a set domain PhD-t ...

                                               

WHSC2

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome WHS is a malformation syndrome associated with a hemizygous ...

                                               

WWC2

WW and C2 domain containing 2 is a protein that in humans is encoded by the WWC2 gene. Though function of WWC2 remains unknown, it has been predicted that WWC2 may play a role in cancer.

                                               

ZGRF1

ZGRF1 is a protein in humans that is encoded by the ZGRF1 gene that has uncharacterised function and a weight of 236.6 kDa. This gene shows relatively low expression in most human tissues, with increased expression in situations of chemical depen ...

                                               

5-HT1A receptor

The serotonin 1A receptor is a subtype of serotonin receptor that binds the neurotransmitter serotonin. It is a G protein-coupled receptor, coupled to the Gi protein, that mediates inhibitory neurotransmission. The serotonin 1A receptor is encode ...

                                               

ABLIM3

The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer. An important paralog of this gene is LIMS1.

                                               

ADAMTS2

A disintegrin and metalloproteinase with thrombospondin motifs 2 also known as procollagen I N-proteinase is an enzyme that in humans is encoded by the ADAMTS2 gene.

                                               

ADAMTS6

This gene encodes a member of the ADAMTS a disintegrin and metalloproteinase with thrombospondin motifs protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a dis ...

                                               

ADAMTS12

A disintegrin and metalloproteinase with thrombospondin motifs 12 is an enzyme that in humans is encoded by the ADAMTS12 gene. This gene encodes a member of the ADAMTS in the disintegrin and metalloproteinase with thrombospondin motifs protein fa ...

                                               

ADCY2

Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase class-3 or guanylyl cyclase family because it contains two guanylate cyclase domains. ADCY2 is ...

                                               

AGGF1

Angiogenic factor with G patch and FHA domains 1 is a protein that in humans is encoded by the AGGF1 gene. AGGF1, is a human gene that acts as an angiogenic factor with G patch and forkhead-associated domain. This gene is expressed primarily in a ...