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ZIC2

Zinc finger protein ZIC2 is a protein that in humans is encoded by the ZIC2 gene. ZIC2 is a member of the Zi nc finger of the c erebellum protein family.

                                               

ACOT1

The ACOT1 gene is located on the 14th chromosome, with its specific localization being 14q24.3. It contains 7 exons. The protein encoded by this gene contains 410 amino acids and forms a homodimer with another chain. Protein contains a star-relat ...

                                               

ADCY4

This gene encodes a member of the family of adenylyl cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate cAMP. Mouse studies show that adenylyl cyclase 4, along wit ...

                                               

ADSSL1 (gene)

This gene encodes a member of the adenylosuccinate synthase family of proteins. The encoded muscle-specific enzyme plays a role in the purine nucleotide cycle by catalyzing the first step in the conversion of inosine monophosphate IMP to adenosin ...

                                               

AKAP5

The A-kinase anchor proteins AKAPs are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A PKA and confining the holoenzyme to discrete locations within the cell. This ...

                                               

AKAP6

A-kinase anchor protein 6 is an enzyme that in humans is encoded by the AKAP6 gene. A-kinase anchor proteins, AKAPs are a group of structurally different proteins that have a common function of binding to the regulatory subunit of protein kinase ...

                                               

Aldehyde dehydrogenase 6 family, member A1

Methylmalonate-semialdehyde dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the ALDH6A1 gene. This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays an important role in valine and pyrimid ...

                                               

Alkb homolog 1, histone h2a dioxygenase

This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and ...

                                               

Alpha 1-antichymotrypsin

Alpha 1-antichymotrypsin is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene.

                                               

Amnionless

A complex of amnionless and cubilin forms the cubam receptor. The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate the functions of bone morphogenetic protein BMP receptor, serving as an accessory or co-re ...

                                               

APEX1

DNA- lyase is an enzyme that in humans is encoded by the APEX1 gene. Sites Apurinic / apyrimidinic AP also called "abasic sites" occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or DNA glycosylases that remove s ...

                                               

ARG2

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists types I and II, this enzyme which differ in their tissue distribution, subcellular localization, immunologic crossreactivity a ...

                                               

ARHGAP5

Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family that may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.

                                               

ASB2

Ankyrin repeat and SOCS box protein 2 is a protein that in humans is encoded by the ASB2 gene. The protein encoded by this gene is a member of the ankyrin repeat and SOC box containing family of ASB proteins. They contain ankyrin repeat sequence ...

                                               

ATP5S

ATP synthase subunit s, mitochondrial is an enzyme that in humans is encoded by the ATP5S gene. This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis using the electrochemical gradient of pr ...

                                               

ATP6V1D

V-type proton ATPase subunit D is an enzyme that in humans is encoded by the ATP6V1D gene. This gene encodes a component vacuolar ATPase V-ATPase, a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase ...

                                               

BAG5

BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene. The protein encoded by this gene is a member СУМКА1-family protein. СУМКА1 is anti-apoptotic protein that functions through interaction with diffe ...

                                               

BAZ1A

The protein encoded by this gene belongs to a family of proteins which includes BAZ1B, BAZ2A, and BAZ2B. All family members contain the following domains and structural motifs: WAKZ motif. (Мотив WAKZ) N-terminus – PHD finger C4HC3 zinc finger. L ...

                                               

BCL2L2

Bcl-2-like protein 2 is a protein that in humans is encoded by the BCL2L2 gene. It was originally discovered by Leonie Gibson, Suzanne Cory and colleagues at the Walter and Eliza Hall Institute of Medical Research, who called it Bcl-w.

                                               

BRF1 (gene)

This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RN ...

                                               

CCDC88C (gene)

This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ domain binding moti ...

                                               

CCDC198

Isoform X2 of CCDC198 is 999 nucleotides long. CCDC198 is notably expressed in both the liver and the kidney. CCDC198 has 296 amino acids and a molecular mass of 34.7 KDA.

                                               

CCNB1IP1

E3 ubiquitin-protein ligase CCNB1IP1 is an enzyme that in humans is encoded by the CCNB1IP1 gene. HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G2 / M. It is a housekeeping gene.

                                               

Cdc42 binding protein kinase beta

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myot ...

                                               

CDKN3

Cyclin-dependent kinase inhibitor 3 is an enzyme that in humans is encoded by the CDKN3 gene. The protein encoded by this gene belongs to the dual specificity protein phosphatase family. He was identified as a cyclin-dependent kinase inhibitor an ...

                                               

CHD8

The gene CHD8 encodes the protein chromodomain helicase DNA binding protein 8, which is a chromatin regulator enzyme that is essential during fetal development. CHD8 is an ATP dependent enzyme. Protein contains the domain Snf2 helicase, which is ...

                                               

Chymase

Chymases are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes. They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal ...

                                               

CIDEB

Cell death-inducing DFFA-like effector b, also known as CIDEB, is a human gene. Recently, CIDEB knockout mice were generated by the method of recombination of homologues. In cide null mice, the reduction of lipogenesis. In CIDEB knockout mice are ...

                                               

CKB (gene)

The protein encoded by this gene, CK-BB, consists of a homodimer of two identical brain-type CK-B subunits. BB-CK is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ...

                                               

CMA1

Chymase is an enzyme that in humans is encoded by the CMA1 gene. This gene product is a chymotryptic serine proteinase that belongs to the family of C1 peptidases. It is expressed in mast cells and thought to function in the degradation of extrac ...

                                               

Cofilin-2

Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Cofilin-2 is a member of the AC group of protei ...

                                               

COQ6

The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 or ubiquinone, which is an essential component of the mitochondrial electron transport ...

                                               

CPNE6

Copine-6 is a protein that in humans is encoded by the CPNE6 gene. This gene encodes a brain-specific member of the family Kopin, which consist of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains an ...

                                               

CRIP1

Cysteine-rich protein 1 is a protein that in humans is encoded by the CRIP1 gene. Cysteine-rich intestinal protein crip belongs to the lim / double protein zinc-finger family, which includes cysteine - glycine rich protein 1 CSRP1, MIM 123876, rh ...

                                               

CRIP2

Cysteine-rich protein 2 is a protein that in humans is encoded by the CRIP2 gene. CRIP2 and is closely related to CRIP1 cysteine-rich protein that contains two lim domains. Intensely expressed during cardiovascular development and to act in order ...

                                               

Cyclin dependent kinase like 1

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

                                               

Cyclin K

The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases CDKs through conformational changes. Activation of ...

                                               

DAAM1

Disheveled-associated activator of morphogenesis 1 is a protein that in humans is encoded by the DAAM1 gene. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

                                               

DAD1

DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift ...

                                               

DDX24

ATP-dependent RNA helicase DDX24 is an enzyme that in humans is encoded by the DDX24 gene. Dead box proteins, characterized by conservative motif ASP-STU-Ala-ASP, dead putative RNA helicase. They are involved in a number of cellular processes, in ...

                                               

DLGAP5

Disks large-associated protein 5 also known as discs large homolog 7 or hepatoma up-regulated protein is a protein that in humans is encoded by the DLGAP5 gene. DLG7 is a kinetochore protein that stabilizes microtubules in the vicinity of chromos ...

                                               

DLK1

Protein delta homolog 1 is a protein that in humans is encoded by the DLK1 gene. It is expressed as a transmembrane protein, but a soluble form cleaved active ADAM17 inhibits adipogenesis, the differentiation of pre-adipocytes to adipocytes. He i ...

                                               

DNAAF2

Kintoun is a highly conserved protein involved in the preassembly of dynein arm complexes which power cilia. These complexes are found in some cilia and are assembled in the cytoplasm prior to transport for ciliogenesis.

                                               

DYNC1H1

Mutations in this gene have been shown to cause dominant axonal Charcot-Marie-Tooth disease as well as spinal muscular atrophy with lower extremity predominance SMA-LED.

                                               

EAPP

E2F-associated phosphoprotein is a protein that in humans is encoded by the EAPP gene. This gene encodes phosphoprotein that interacts with several members of the e2f family of proteins. This protein is localized in the nucleus, and is present th ...

                                               

EGLN3

Egl nine homolog 3 is a protein that in humans is encoded by the EGLN3 gene. ELGN3 is a member of the superfamily of alpha-ketoglutarate-dependent hydroxylases, which are non-haem iron-containing proteins.

                                               

EIF2B2

Eukaryotic initiation factor-2B EIF2B is a GTP exchange protein essential for protein synthesis. It consists of alpha EIF2B1, MIM 606686, beta EIF2B2, gamma EIF2B3, MIM 606273, delta EIF2B4, MIM 606687, and epsilon EIF2B5, MIM 603945 subunits. EI ...

                                               

EIF2S1

The protein encoded by this gene is the alpha α subunit of the translation initiation factor eIF2 complex which catalyzes an early regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA Met-tRNA i Met to 40S r ...

                                               

EML1

Echinoderm microtubule-associated protein-like 1 is a protein that in humans is encoded by the EML1 gene. Microtubule-associated protein echinoderms person is a strong candidate for the usher syndrome type 1A gene. Usher syndromes OSS is a group ...

                                               

ENTPD5

Ectonucleoside triphosphate diphosphohydrolase 5 is an enzyme that in humans is encoded by the ENTPD5 gene. ENTPD5 is similar to e-type nucleotidases NTPases / ecto-ATPase / apyrases. NTPases, such as CD39, mediate catabolism of extracellular nuc ...